Phenotypes associated with this allele

• Allele Symbol: Tinagl1^tm1.1Maru
• Allele Name: targeted mutation 1.1, Hiromichi Matsumoto
• Allele ID: MGI:6153214
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tinagl1^tm1.1Maru/Tinagl1^tm1.1Maru	involves: 129S2/SvPas * C57BL/6NSlc	MGI:6157819

Genotype
MGI:6157819

hm1

• Allelic Composition: Tinagl1^tm1.1Maru/Tinagl1^tm1.1Maru
• Genetic Background: involves: 129S2/SvPas * C57BL/6NSlc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:260681 )

• pups from homozygous mothers may die within 7 days of birth (in 28 of 138 matings)

reproductive system

reproductive system phenotype ( J:260681 )

N • male fertility is not impaired

N • response to superovulation, fertilization capability and competence of ovulated oocytes are similar to controls

reduced female fertility ( J:260681 )

♀ • some matings result in either no plug (24 of 138), absence of placental sign despite presence of a plug (15 of 138) or no delivery (3 of 138)