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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nf1tm2.1Kest
targeted mutation 2.1, Robert A Kesterson
MGI:6153137
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nf1tm2.1Kest/Nf1tm2.1Kest involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6NTac MGI:6275133
ht2
Nf1tm1d(KOMP)Wtsi/Nf1tm2.1Kest involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * FVB/N MGI:6275188


Genotype
MGI:6275133
hm1
Allelic
Composition
Nf1tm2.1Kest/Nf1tm2.1Kest
Genetic
Background
involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf1tm2.1Kest mutation (0 available); any Nf1 mutation (157 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are viable and indistinguishable from heterozygotes, do not develop tumors in the spinal columns or peripheral nerves, and do not show disruption of myelinated or non-myelinated axons




Genotype
MGI:6275188
ht2
Allelic
Composition
Nf1tm1d(KOMP)Wtsi/Nf1tm2.1Kest
Genetic
Background
involves: 129S4/SvJaeSor * C57BL/6 * C57BL/6N * FVB/N
Cell Lines EPD0033_1_F12
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nf1tm1d(KOMP)Wtsi mutation (0 available); any Nf1 mutation (157 available)
Nf1tm2.1Kest mutation (0 available); any Nf1 mutation (157 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice are viable and display no overt phenotype, with no tumor development up to 24 months of age





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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory