Phenotypes associated with this allele

• Allele Symbol: Sfr1^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6152635
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sfr1^em1(IMPC)Mbp/Sfr1^em1(IMPC)Mbp	C57BL/6NCrl-Sfr1^em1(IMPC)Mbp/Mmucd	MGI:6263460
ht2	Sfr1^em1(IMPC)Mbp/Sfr1^+	C57BL/6NCrl-Sfr1^em1(IMPC)Mbp/Mmucd	MGI:6394382

Genotype
MGI:6263460

hm1

• Allelic Composition: Sfr1^em1(IMPC)Mbp/Sfr1^em1(IMPC)Mbp
• Genetic Background: C57BL/6NCrl-Sfr1^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Sfr1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

♀

IMPC - UCD

abnormal embryo size ( J:211773 )

IMPC - UCD

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal somite shape ( J:211773 )

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

♀

IMPC - UCD

abnormal embryo size ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

Genotype
MGI:6394382

ht2

• Allelic Composition: Sfr1^em1(IMPC)Mbp/Sfr1⁺
• Genetic Background: C57BL/6NCrl-Sfr1^em1(IMPC)Mbp/Mmucd

Data Sources

IMPC Data for Sfr1

homeostasis/metabolism

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - UCD