Phenotypes associated with this allele

• Allele Symbol: Armc2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6148226
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Armc2^tm1b(EUCOMM)Hmgu/Armc2^tm1b(EUCOMM)Hmgu	C57BL/6N-Armc2^tm1b(EUCOMM)Hmgu/H	MGI:6261908
ht2	Armc2^tm1b(EUCOMM)Hmgu/Armc2^+	C57BL/6N-Armc2^tm1b(EUCOMM)Hmgu/H	MGI:6288341

Genotype
MGI:6261908

hm1

• Allelic Composition: Armc2^{tm1b(EUCOMM)Hmgu}/Armc2^{tm1b(EUCOMM)Hmgu}
• Genetic Background: C57BL/6N-Armc2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0895_4_B05

Data Sources

IMPC Data for Armc2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6288341

ht2

• Allelic Composition: Armc2^{tm1b(EUCOMM)Hmgu}/Armc2⁺
• Genetic Background: C57BL/6N-Armc2^{tm1b(EUCOMM)Hmgu}/H
• Cell Lines: HEPD0895_4_B05

Data Sources

IMPC Data for Armc2

hematopoietic system

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

decreased circulating fructosamine level ( J:211773 )

♂

IMPC - HAR

increased circulating alanine transaminase level ( J:211773 )

♂

IMPC - HAR

increased circulating aspartate transaminase level ( J:211773 )

♂

IMPC - HAR

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - HAR

immune system

increased neutrophil cell number ( J:211773 )

♂

IMPC - HAR

decreased lymphocyte cell number ( J:211773 )

♂

IMPC - HAR