About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adamts16em2(IMPC)H
endonuclease-mediated mutation 2, Harwell
MGI:6140145
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adamts16em2(IMPC)H/Adamts16em2(IMPC)H C57BL/6NTac-Adamts16em2(IMPC)H MGI:7260117


Genotype
MGI:7260117
hm1
Allelic
Composition		 Adamts16em2(IMPC)H/Adamts16em2(IMPC)H
Genetic
Background		 C57BL/6NTac-Adamts16em2(IMPC)H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts16em2(IMPC)H mutation (1 available); any Adamts16 mutation (83 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:283272 )
N
• unexpectedly, male mice undergo normal primary sex determination and develop testes in the fetal period; adult males have no defects in testicular descent and show normal fertility at 3 and 6 months of age
• female mice are also fertile with no apparent morphological defects in the reproductive system
decreased testis weight ( J:283272 )
• adult males show a small but significant (~10%) decrease in average testis weight relative to age-matched controls
• however, adult testicular histology is normal

endocrine/exocrine glands
decreased testis weight ( J:283272 )
• adult males show a small but significant (~10%) decrease in average testis weight relative to age-matched controls
• however, adult testicular histology is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory