Phenotypes associated with this allele

• Allele Symbol: Lpp^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6120784
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lpp^tm1b(KOMP)Wtsi/Lpp^tm1b(KOMP)Wtsi	C57BL/6NCrl-Lpp^tm1b(KOMP)Wtsi/Ccpcz	MGI:7414955
ht2	Lpp^tm1b(KOMP)Wtsi/Lpp^+	C57BL/6NCrl-Lpp^tm1b(KOMP)Wtsi/Ccpcz	MGI:7414954

Genotype
MGI:7414955

hm1

• Allelic Composition: Lpp^{tm1b(KOMP)Wtsi}/Lpp^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6NCrl-Lpp^{tm1b(KOMP)Wtsi}/Ccpcz
• Cell Lines: EPD0859_5_F01

Data Sources

IMPC Data for Lpp

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal retina vasculature morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

homeostasis/metabolism

decreased circulating HDL cholesterol level ( J:211773 )

IMPC - HMGU

liver/biliary system

abnormal liver morphology ( J:211773 )

IMPC - HMGU

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - HMGU

nervous system

abnormal optic disk morphology ( J:211773 )

♀

IMPC - HMGU

vision/eye

abnormal optic disk morphology ( J:211773 )

♀

IMPC - HMGU

persistence of hyaloid vascular system ( J:211773 )

♀

IMPC - HMGU

abnormal retina morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina vasculature morphology ( J:211773 )

♀

IMPC - HMGU

abnormal retina blood vessel morphology ( J:211773 )

♀

IMPC - HMGU

Genotype
MGI:7414954

ht2

• Allelic Composition: Lpp^{tm1b(KOMP)Wtsi}/Lpp⁺
• Genetic Background: C57BL/6NCrl-Lpp^{tm1b(KOMP)Wtsi}/Ccpcz
• Cell Lines: EPD0859_5_F01

Data Sources

IMPC Data for Lpp

homeostasis/metabolism

increased circulating phosphate level ( J:211773 )

♀

IMPC - HMGU