Phenotypes associated with this allele

• Allele Symbol: Trpm7^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:6120763
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trpm7^tm1b(KOMP)Wtsi/Trpm7^tm1b(KOMP)Wtsi	C57BL/6N-Trpm7^tm1b(KOMP)Wtsi/H	MGI:6263783
ht2	Trpm7^tm1b(KOMP)Wtsi/Trpm7^+	C57BL/6N-Trpm7^tm1b(KOMP)Wtsi/H	MGI:6263782

Genotype
MGI:6263783

hm1

• Allelic Composition: Trpm7^{tm1b(KOMP)Wtsi}/Trpm7^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Trpm7^{tm1b(KOMP)Wtsi}/H
• Cell Lines: EPD0655_2_D07

Data Sources

IMPC Data for Trpm7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - HAR

preweaning lethality, complete penetrance ( J:211773 )

IMPC - HAR

Genotype
MGI:6263782

ht2

• Allelic Composition: Trpm7^{tm1b(KOMP)Wtsi}/Trpm7⁺
• Genetic Background: C57BL/6N-Trpm7^{tm1b(KOMP)Wtsi}/H
• Cell Lines: EPD0655_2_D07

Data Sources

IMPC Data for Trpm7

hematopoietic system

thrombocytosis ( J:211773 )

♂

IMPC - HAR

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - HAR

vision/eye

abnormal iris morphology ( J:211773 )

IMPC - HAR

abnormal placement of pupils ( J:211773 )

♂

IMPC - HAR

irregularly shaped pupil ( J:211773 )

IMPC - HAR

cornea opacity ( J:211773 )

IMPC - HAR