All Phenotypes Lacc1<em1Arkr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Lacc1^em1Arkr
endonuclease-mediated mutation 1, Arthur Kaser
MGI:6117843

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lacc1^em1Arkr/Lacc1^em1Arkr	C57BL/6NTac-Lacc1^em1Arkr	MGI:6118079

Allelic Composition	Lacc1^em1Arkr/Lacc1^em1Arkr
Genetic Background	C57BL/6NTac-Lacc1^em1Arkr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lacc1^em1Arkr mutation (0 available); any Lacc1 mutation (26 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal macrophage physiology ( J:244365 )

• macrophages exhibit increased basal or maximal uncontrolled oxygen consumption rate compared with wild-type cells

• macrophages exhibit an increased in glycolysis compared with wild-type mice

homeostasis/metabolism

cellular

abnormal redox activity ( J:244365 )

hematopoietic system

abnormal macrophage physiology ( J:244365 )

• macrophages exhibit increased basal or maximal uncontrolled oxygen consumption rate compared with wild-type cells

• macrophages exhibit an increased in glycolysis compared with wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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