About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Upf3atm1.2Wilk
targeted mutation 1.2, Miles F Wilkinson
MGI:6117430
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Upf3atm1.2Wilk/Upf3atm1.2Wilk involves: 129 * C57BL/6 MGI:6117758
ht2
 		Upf3atm1.2Wilk/Upf3a+ involves: 129 * C57BL/6 MGI:6117759


Genotype
MGI:6117758
hm1
Allelic
Composition		 Upf3atm1.2Wilk/Upf3atm1.2Wilk
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Upf3atm1.2Wilk mutation (0 available); any Upf3a mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryo morphology ( J:234504 )
• defects observed starting at E3.5

mortality/aging
embryonic lethality, complete penetrance ( J:234504 )
• embryos die between E4.5 and E8.5




Genotype
MGI:6117759
ht2
Allelic
Composition		 Upf3atm1.2Wilk/Upf3a+
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Upf3atm1.2Wilk mutation (0 available); any Upf3a mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:234504 )
N
• viable




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory