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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chchd10em5Lutzy
endonuclease-mediated mutation 5, Cathy Lutz
MGI:6117383
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Chchd10em5Lutzy/Chchd10em5Lutzy C57BL/6J-Chchd10em5Lutzy/J MGI:6118199


Genotype
MGI:6118199
hm1
Allelic
Composition		 Chchd10em5Lutzy/Chchd10em5Lutzy
Genetic
Background		 C57BL/6J-Chchd10em5Lutzy/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chchd10em5Lutzy mutation (1 available); any Chchd10 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal heart ventricle morphology ( J:254726 )
• electron dense round structures are observed between sarcomeres in the right ventricle wall

cellular
cellular phenotype ( J:254726 )
N
• mitochondria exhibit no differences in oxygen consumption or ATP synthesis
• no ultrastructural abnormalities are observed in the mitochondria
abnormal respiratory electron transport chain ( J:254726 )
• mitochondria from skeletal muscle exhibit decreased ADP-stimulated respiration




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory