All Phenotypes Tdrd5<tm1c(EUCOMM)Hmgu> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tdrd5^{tm1c(EUCOMM)Hmgu}
targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
MGI:6115347

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Tdrd5^{tm1c(EUCOMM)Hmgu}/Tdrd5^{tm1c(EUCOMM)Hmgu} Tg(Stra8-icre)1Reb/0	involves: C57BL/6N * FVB/NJ	MGI:6156877

Allelic Composition	Tdrd5^{tm1c(EUCOMM)Hmgu}/Tdrd5^{tm1c(EUCOMM)Hmgu} Tg(Stra8-icre)1Reb/0
Genetic Background	involves: C57BL/6N * FVB/NJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tdrd5^{tm1c(EUCOMM)Hmgu} mutation (0 available); any Tdrd5 mutation (40 available)
Tg(Stra8-icre)1Reb mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

decreased testis weight ( J:255733 )

• average 50% reduction

testicular atrophy ( J:255733 )

• average 50% of wild-type weight

reproductive system

decreased testis weight ( J:255733 )

• average 50% reduction

testicular atrophy ( J:255733 )

• average 50% of wild-type weight

arrest of spermatogenesis ( J:255733 )

• at round spermatid stage; no elongating spermatids or spermatozoa formed

male infertility ( J:255733 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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