Phenotypes associated with this allele

• Allele Symbol: Tg(tetO-Vegfa)1Ywz
• Allele Name: transgene insertion 1, Yaowu Zheng
• Allele ID: MGI:6115016
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(ACTB-tetR*)19Ywz/0 Tg(tetO-Vegfa)1Ywz/0	involves: 129S1/Sv * 129X1/SvJ	MGI:6115295

Genotype
MGI:6115295

cx1

• Allelic Composition: Tg(ACTB-tetR*)19Ywz/0; Tg(tetO-Vegfa)1Ywz/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:189035 )

♀ • in female mice withdrawn from doxycycline with a not statistically significant trend in male mice compared with doxycycline-fed mice

decreased susceptibility to diet-induced obesity ( J:189035 )

• in female and male mice withdrawn from doxycycline compared with doxycycline-fed mice

adipose tissue

browned white adipose tissue morphology ( J:189035 )

• mice withdrawn from doxycycline exhibit decreased lipid droplet size and increased cell number in gonadal white adipose tissue adipose compared with doxycycline-fed mice on a high-fat diet

behavior/neurological

decreased food intake ( J:189035 )

♀ • in female and male mice withdrawn from doxycycline compared with doxycycline-fed mice

homeostasis/metabolism

decreased susceptibility to diet-induced obesity ( J:189035 )

• in female and male mice withdrawn from doxycycline compared with doxycycline-fed mice