All Phenotypes Prkdc<m7Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prkdc^m7Btlr
mutation 7, Bruce Beutler
MGI:6114147

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkdc^m7Btlr/Prkdc^m7Btlr	C57BL/6J-Prkdc^m7Btlr	MGI:6114150

Allelic Composition	Prkdc^m7Btlr/Prkdc^m7Btlr
Genetic Background	C57BL/6J-Prkdc^m7Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkdc^m7Btlr mutation (0 available); any Prkdc mutation (408 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

abnormal humoral immune response ( J:255223 )

• diminished T-dependent humoral response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

decreased IgG level ( J:255223 )

• diminished T-dependent humoral response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

hematopoietic system

decreased IgG level ( J:255223 )

• diminished T-dependent humoral response to recombinant Semliki Forest virus (rSFV)-encoded beta-galactosidase (rSFV-beta-gal)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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