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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkdcm6Btlr
mutation 6, Bruce Beutler
MGI:6114136
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prkdcm6Btlr/Prkdcm6Btlr C57BL/6J-Prkdcm6Btlr MGI:6114139


Genotype
MGI:6114139
hm1
Allelic
Composition		 Prkdcm6Btlr/Prkdcm6Btlr
Genetic
Background		 C57BL/6J-Prkdcm6Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkdcm6Btlr mutation (0 available); any Prkdc mutation (399 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased CD8-positive, naive alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection
increased alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection
increased CD4-positive, alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection
increased CD8-positive, alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection

hematopoietic system
decreased CD8-positive, naive alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection
increased alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection
increased CD4-positive, alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection
increased CD8-positive, alpha-beta T cell number ( J:255221 )
• after mouse cytomegalovirus (MCMV) infection




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory