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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ighdm2Btlr
mutation 2, Bruce Beutler
MGI:6114054
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ighdm2Btlr/Ighdm2Btlr C57BL/6J-Ighdm2Btlr MGI:6114056
ht2
 		Ighdm2Btlr/Ighd+ C57BL/6J-Ighdm2Btlr MGI:6114057


Genotype
MGI:6114056
hm1
Allelic
Composition		 Ighdm2Btlr/Ighdm2Btlr
Genetic
Background		 C57BL/6J-Ighdm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighdm2Btlr mutation (0 available); any Ighd mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood
decreased IgD level ( J:255203 )
• reduced expression of IgD on peripheral blood B cells

immune system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood
decreased IgD level ( J:255203 )
• reduced expression of IgD on peripheral blood B cells




Genotype
MGI:6114057
ht2
Allelic
Composition		 Ighdm2Btlr/Ighd+
Genetic
Background		 C57BL/6J-Ighdm2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighdm2Btlr mutation (0 available); any Ighd mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood

hematopoietic system
decreased B cell number ( J:255203 )
• reduction percentage of IgD+ B cells in the peripheral blood




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory