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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		IghdM1Btlr
mutation 1, Bruce Beutler
MGI:6114049
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		IghdM1Btlr/IghdM1Btlr C57BL/6J-IghdM1Btlr MGI:6114051
ht2
 		IghdM1Btlr/Ighd+ C57BL/6J-IghdM1Btlr MGI:6114052


Genotype
MGI:6114051
hm1
Allelic
Composition		 IghdM1Btlr/IghdM1Btlr
Genetic
Background		 C57BL/6J-IghdM1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
IghdM1Btlr mutation (0 available); any Ighd mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B cell number ( J:255202 )
• in the peripheral blood
decreased IgD level ( J:255202 )
• reduced expression of IgD on peripheral blood B cells

hematopoietic system
decreased B cell number ( J:255202 )
• in the peripheral blood
decreased IgD level ( J:255202 )
• reduced expression of IgD on peripheral blood B cells




Genotype
MGI:6114052
ht2
Allelic
Composition		 IghdM1Btlr/Ighd+
Genetic
Background		 C57BL/6J-IghdM1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
IghdM1Btlr mutation (0 available); any Ighd mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased B cell number ( J:255202 )
• in the peripheral blood

hematopoietic system
decreased B cell number ( J:255202 )
• in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory