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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Foxi2tm1.1Akg
targeted mutation 1.1, Andrew K Groves
MGI:6113414
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Foxi2tm1.1Akg/Foxi2tm1.1Akg involves: BALB/cJ MGI:6114102
cx2
 		Foxi2tm1.1Akg/Foxi2tm1.1Akg
Foxi3tm1.2Akg/Foxi3tm1.2Akg 		involves: 129X1/SvJ * BALB/cJ MGI:6114103


Genotype
MGI:6114102
hm1
Allelic
Composition		 Foxi2tm1.1Akg/Foxi2tm1.1Akg
Genetic
Background		 involves: BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxi2tm1.1Akg mutation (0 available); any Foxi2 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:228880 )
• viable and fertile with no gross abnormalities




Genotype
MGI:6114103
cx2
Allelic
Composition		 Foxi2tm1.1Akg/Foxi2tm1.1Akg
Foxi3tm1.2Akg/Foxi3tm1.2Akg
Genetic
Background		 involves: 129X1/SvJ * BALB/cJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxi2tm1.1Akg mutation (0 available); any Foxi2 mutation (20 available)
Foxi3tm1.2Akg mutation (0 available); any Foxi3 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal nervous system development ( J:228880 )
• no significant difference from mice homozygous null for Foxi3 alone
abnormal vestibulocochlear ganglion morphology ( J:228880 )
• absent or severely deformed
abnormal geniculate ganglion morphology ( J:228880 )
• absent or severely deformed
abnormal trigeminal ganglion morphology ( J:228880 )
• absence of the mandibular branch of the trigeminal ganglion
• however, the ophthalmic and maxillary branches remain




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory