All Phenotypes Pias3<tm1.2Asw> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pias3^tm1.2Asw
targeted mutation 1.2, Anand Swaroop
MGI:5927688

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Pias3^tm1.2Asw/Pias3^tm1.2Asw Tg(rx3-icre)1Mjam/0	involves: C57BL/6J * SJL	MGI:5927698

Allelic Composition	Pias3^tm1.2Asw/Pias3^tm1.2Asw Tg(rx3-icre)1Mjam/0
Genetic Background	involves: C57BL/6J * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pias3^tm1.2Asw mutation (0 available); any Pias3 mutation (39 available)
Tg(rx3-icre)1Mjam mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal cone electrophysiology ( J:243503 )

• M-cone response to green light flashes in light-adapted P21 mice as measured with ERG was significantly reduced and remained reduced till at least 12 months old

• S-cone response to UV light flashes in light-adapted mice as measured with ERG started reducing from 7 months old

abnormal rod electrophysiology ( J:243503 )

• response to a- and b-waves in dark-adapted mice as measured with ERG started reducing from 7 months old

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