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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gt(ROSA)26Sortm1(Bcor*A)Vjba
targeted mutation 1, Vivian J Bardwell
MGI:5925311
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Gt(ROSA)26Sortm1(Bcor*A)Vjba/Gt(ROSA)26Sortm1(Bcor*A)Vjba involves: 129S1/Sv MGI:5925313
cn2
Gt(ROSA)26Sortm1(Bcor*A)Vjba/Gt(ROSA)26Sor+
Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
involves: 129S1/Sv * FVB/N MGI:7344054


Genotype
MGI:5925313
cn1
Allelic
Composition
Gt(ROSA)26Sortm1(Bcor*A)Vjba/Gt(ROSA)26Sortm1(Bcor*A)Vjba
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Bcor*A)Vjba mutation (1 available); any Gt(ROSA)26Sor mutation (944 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• bone marrow cells cultured under myeloid stem/progenitor conditions and infected with a cre expression retrovirus exhibit decreased proliferative rate

hematopoietic system
• bone marrow cells cultured under myeloid stem/progenitor conditions and infected with a cre expression retrovirus exhibit decreased proliferative rate




Genotype
MGI:7344054
cn2
Allelic
Composition
Gt(ROSA)26Sortm1(Bcor*A)Vjba/Gt(ROSA)26Sor+
Tmem163Tg(ACTB-cre)2Mrt/Tmem163+
Genetic
Background
involves: 129S1/Sv * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Bcor*A)Vjba mutation (1 available); any Gt(ROSA)26Sor mutation (944 available)
Tmem163Tg(ACTB-cre)2Mrt mutation (3 available); any Tmem163 mutation (35 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• embryos die between E10.5 and E14.5 with all dead by E14.5

craniofacial
• short and misshapen
• short and misshapen

vision/eye
• misshapen by E12.5

limbs/digits/tail
• small and misshapen by E13.5

nervous system
• appears bulbous

skeleton
• short and misshapen

growth/size/body
• short and misshapen





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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory