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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Thy1-tTA)15Lmit
transgene insertion 15, Lars M Ittner
MGI:5922014
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(tetO-TARDBP*A315T)13Lmit/0
Tg(Thy1-tTA)15Lmit/0 		involves: C57BL/6 MGI:6095190
cx2
 		Tg(tetO-TARDBP*A315T)6Lmit/0
Tg(Thy1-tTA)15Lmit/0 		involves: C57BL/6 MGI:6095192


Genotype
MGI:6095190
cx1
Allelic
Composition		 Tg(tetO-TARDBP*A315T)13Lmit/0
Tg(Thy1-tTA)15Lmit/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
impaired coordination ( J:245760 )
• 3 month old mice show motor impairments during pole testing

nervous system
hippocampal neuron degeneration ( J:245760 )
• degeneration of the hippocampus, in particular of the CA1 region, at 9 months of age




Genotype
MGI:6095192
cx2
Allelic
Composition		 Tg(tetO-TARDBP*A315T)6Lmit/0
Tg(Thy1-tTA)15Lmit/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
hippocampal neuron degeneration ( J:245760 )
• degeneration of the hippocampus by 4 weeks of age




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory