Phenotypes associated with this allele

• Allele Symbol: Nlrp9b^em1Flv
• Allele Name: endonuclease-mediated mutation 1, Richard Flavell
• Allele ID: MGI:5910440
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nlrp9b^em1Flv/Nlrp9b^em1Flv	C57BL/6N-Nlrp9b^em1Flv	MGI:6106863

Genotype
MGI:6106863

hm1

• Allelic Composition: Nlrp9b^em1Flv/Nlrp9b^em1Flv
• Genetic Background: C57BL/6N-Nlrp9b^em1Flv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:243487 )

• increased sensitivity to and pathology of oral rotavirus inoculation

• after oral rotavirus inoculation of 8 day old pups

• elevated viral load in intestinal epithelial cells (IECs)

• fecal antigen shedding

mortality/aging

increased susceptibility to Riboviria infection induced morbidity/mortality ( J:243487 )

• increased sensitivity to and pathology of oral rotavirus inoculation

• after oral rotavirus inoculation of 8 day old pups

• elevated viral load in intestinal epithelial cells (IECs)

• fecal antigen shedding

cellular

decreased apoptosis ( J:243487 )

• of intestinal epithelial cells (IECs) after oral rotavirus inoculation of 8 day old pups

digestive/alimentary system

diarrhea ( J:243487 )

• increased occurrence after oral rotavirus inoculation of 8 day old pups