All Phenotypes Tnfrsf14<tm1Kro> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tnfrsf14^tm1Kro
targeted mutation 1, Mitchell Kronenberg
MGI:5908456

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tnfrsf14^tm1Kro/Tnfrsf14^tm1Kro	C57BL/6-Tnfrsf14^tm1Kro	MGI:5908554

Allelic Composition	Tnfrsf14^tm1Kro/Tnfrsf14^tm1Kro
Genetic Background	C57BL/6-Tnfrsf14^tm1Kro

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfrsf14^tm1Kro mutation (0 available); any Tnfrsf14 mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased susceptibility to Herpesvirales infection ( J:243038 )

• following corneal inoculation of HSV1, corneas do not become as heavily infiltrated with CD45+ leukocytes as do controls

behavior/neurological

abnormal blinking ( J:243038 )

• following corneal inoculation of HSV1, corneal reflexes (as measured by corneal touch threshold) are largely retained in contrast to infected controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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