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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chaer1em1Holi
endonuclease-mediated mutation 1, Hongliang Li
MGI:5905817
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Chaer1em1Holi/Chaer1em1Holi C57BL/6-Chaer1em1Holi MGI:5906131


Genotype
MGI:5906131
hm1
Allelic
Composition		 Chaer1em1Holi/Chaer1em1Holi
Genetic
Background		 C57BL/6-Chaer1em1Holi
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
decreased response of heart to induced stress ( J:240516 )
• attenuated hypertrophic response to surgically induced pressure overloading
• reduced fibrosis in response to surgically induced pressure overloading

homeostasis/metabolism
decreased response of heart to induced stress ( J:240516 )
• attenuated hypertrophic response to surgically induced pressure overloading
• reduced fibrosis in response to surgically induced pressure overloading




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory