All Phenotypes Mettl8<em1Nju> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mettl8^em1Nju
endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
MGI:5903742

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mettl8^em1Nju/Mettl8^em1Nju	Not Specified	MGI:5903745

Allelic Composition	Mettl8^em1Nju/Mettl8^em1Nju
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettl8^em1Nju mutation (0 available); any Mettl8 mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

mortality/aging ( J:241777 )

N	• normal Mendel ratio without observable developmental defects

cellular

abnormal cell physiology ( J:241777 )

• liver tissue exhibits reduced 3-methylcytidine (m3C) methyltransferases modification of mRNA compared with in wild-type mice

• however, tRNA m3C is normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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