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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mettl2em1Nju
endonuclease-mediated mutation 1, Model Animal Research Center of Nanjing University
MGI:5903740
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mettl2em1Nju/Mettl2em1Nju Not Specified MGI:5903743


Genotype
MGI:5903743
hm1
Allelic
Composition		 Mettl2em1Nju/Mettl2em1Nju
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettl2em1Nju mutation (0 available); any Mettl2 mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:241777 )
N
• normal Mendel ratio without observable developmental defects

cellular
abnormal cell physiology ( J:241777 )
• brain and liver tissue exhibit reduced 3-methylcytidine (m3C) methyltransferases modification of tRNA compared with in wild-type mice
• however, mRNA m3C is normal in the liver




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory