All Phenotypes Cdh23<tm2.1Kjn> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cdh23^tm2.1Kjn
targeted mutation 2.1, Kenneth R Johnson
MGI:5897995

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdh23^tm2.1Kjn/Cdh23^tm2.1Kjn	B6N(Cg)-Cdh23^tm2.1Kjn/Kjn	MGI:5898129

Allelic Composition	Cdh23^tm2.1Kjn/Cdh23^tm2.1Kjn
Genetic Background	B6N(Cg)-Cdh23^tm2.1Kjn/Kjn

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh23^tm2.1Kjn mutation (1 available); any Cdh23 mutation (280 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:241137 )

N	• The severe outer and inner hair cell loss phenotype is rescued by this revertant allele, and normal ABR thresholds are found up through 18 months of age at 16 kHz and 32 kHz, but low frequency hearing loss, 8 kHz, normally found on this genetic background still occurs.

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