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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Myh6-Atp1a2)1Jmol
transgene insertion 1, Jeffery Molkentin
MGI:5897332
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Myh6-Atp1a2)1Jmol/0 involves: FVB MGI:5897351


Genotype
MGI:5897351
tg1
Allelic
Composition
Tg(Myh6-Atp1a2)1Jmol/0
Genetic
Background
involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Myh6-Atp1a2)1Jmol mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• following transverse aortic constriction to induce pressure overload hypertrophy
• following transverse aortic constriction to induce pressure overload hypertrophy
• following transverse aortic constriction to induce pressure overload hypertrophy, mice exhibit reduced ventricular weight with reduced myocyte cross-sectional area and reduced lung weight compared with wild-type mice

homeostasis/metabolism
• following transverse aortic constriction to induce pressure overload hypertrophy, mice exhibit reduced ventricular weight with reduced myocyte cross-sectional area and reduced lung weight compared with wild-type mice

muscle
• following transverse aortic constriction to induce pressure overload hypertrophy

respiratory system
• following transverse aortic constriction to induce pressure overload hypertrophy





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory