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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nraddtm1.2Pabk
targeted mutation 1.2, Philip A Barker
MGI:5888871
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nraddtm1.2Pabk/Nraddtm1.2Pabk B6.129-Nraddtm1.2Pabk MGI:5896413


Genotype
MGI:5896413
hm1
Allelic
Composition
Nraddtm1.2Pabk/Nraddtm1.2Pabk
Genetic
Background
B6.129-Nraddtm1.2Pabk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nraddtm1.2Pabk mutation (0 available); any Nradd mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
N
• adult mice are viable, fertile and overtly indistinguishable from wild-type controls with normal weight gain up to 80 days of age
• interestingly, adult mice show a 40% increase in the proportion of dorsal root ganglion (DRG) sensory neurons that express NGFR (also known as p75NTR); however, the total number of sensory neurons in L4 DRG is similar to that in wild-type controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory