About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Stub1em1Schiz
endonuclease-mediated mutation 1, Jonathan Schisler
MGI:5883530
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Stub1em1Schiz/Stub1em1Schiz C57BL/6J-Stub1em1Schiz MGI:6154591


Genotype
MGI:6154591
hm1
Allelic
Composition
Stub1em1Schiz/Stub1em1Schiz
Genetic
Background
C57BL/6J-Stub1em1Schiz
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stub1em1Schiz mutation (0 available); any Stub1 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• cumulative fluid intake is lower than in controls

homeostasis/metabolism
• increase in urine chloride level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine potassium concentration
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine sodium level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• urine osmolality is higher than in controls
• however, baseline serum electrolytes are normal
• increase in urine baseline urea level
• however, when normalized to creatinine, no differences are seen

renal/urinary system
• increase in urine chloride level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine potassium concentration
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• increase in urine sodium level
• however, when urinary electrolyte concentrations are normalized to creatinine, no differences are seen
• urine osmolality is higher than in controls
• however, baseline serum electrolytes are normal
• increase in urine baseline urea level
• however, when normalized to creatinine, no differences are seen





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory