Phenotypes associated with this allele

• Allele Symbol: Repin1^tm1.2Arte
• Allele Name: targeted mutation 1.2, TaconicArtemis
• Allele ID: MGI:5882542
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Lepr^db/Lepr^db Repin1^tm1.2Arte/Repin1^tm1.2Arte	involves: BALB/c * C57BL/6 * C57BLKS/J	MGI:5903475

Genotype
MGI:5903475

cx1

• Allelic Composition: Lepr^db/Lepr^db; Repin1^tm1.2Arte/Repin1^tm1.2Arte
• Genetic Background: involves: BALB/c * C57BL/6 * C57BLKS/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body fat mass ( J:238672 )

• at 20 weeks compared with Lepr^db homozygotes

decreased body weight ( J:238672 )

• at 8 to 20 weeks compared with Lepr^db homozygotes

• however, body length is normal

adipose tissue

decreased body fat mass ( J:238672 )

• at 20 weeks compared with Lepr^db homozygotes

abnormal adipose tissue physiology ( J:238672 )

• reduced inflammatory infiltrate compared with Lepr^db homozygotes

homeostasis/metabolism

decreased circulating glucose level ( J:238672 )

• compared with Lepr^db homozygotes

increased insulin sensitivity ( J:238672 )

• compared with Lepr^db homozygotes