All Phenotypes Baiap2l1<tm1Zgh> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Baiap2l1^tm1Zgh
targeted mutation 1, Ze-Guang Han
MGI:5828650

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Baiap2l1^tm1Zgh/Baiap2l1^tm1Zgh	B6.Cg-Baiap2l1^tm1Zgh	MGI:5828738

Allelic Composition	Baiap2l1^tm1Zgh/Baiap2l1^tm1Zgh
Genetic Background	B6.Cg-Baiap2l1^tm1Zgh

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baiap2l1^tm1Zgh mutation (0 available); any Baiap2l1 mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

increased fasting circulating glucose level ( J:238622 )

• in male and female mice

increased circulating insulin level ( J:238622 )

impaired glucose tolerance ( J:238622 )

increased hepatic glucose production ( J:238622 )

• in hyper-insulinemic-euglycemic clamp studies

• however, glucose disappearance rates are normal

insulin resistance ( J:238622 )

• however, ectopic expression of the endogenous gene reverses insulin resistance

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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