All Phenotypes pwhl MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

pwhl
pinwheel
MGI:5825368

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	pwhl/pwhl	B6.Cg-pwhl/KjnJ	MGI:5825452

Allelic Composition	pwhl/pwhl
Genetic Background	B6.Cg-pwhl/KjnJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
pwhl mutation (1 available); any pwhl mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired swimming ( J:239145 )

• homozygotes fail to orient in water, consistent with a vestibular defect

bidirectional circling ( J:239145 )

• female and male homozygotes display bidirectional circling

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:239145 )

N	• despite the vestibular defect, auditory brainstem response analysis found no hearing loss in homozygotes relative to age matched controls

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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