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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tyrem12Ove
endonuclease-mediated mutation 12, Paul Overbeek
MGI:5818889
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		A/?
Tyrem12Ove/Tyrem12Ove 		involves: C57BL/6 * FVB MGI:5818890
cx2
 		A/?
Tyrc/Tyrem12Ove 		involves: C57BL/6 * FVB MGI:5822839


Genotype
MGI:5818890
cx1
Allelic
Composition		 A/?
Tyrem12Ove/Tyrem12Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
Tyrem12Ove mutation (1 available); any Tyr mutation (376 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• the fur of mice homozygous for this Tyr mutation on an agouti background appears light brown

pigmentation
diluted coat color ( J:94077 )
• the fur of mice homozygous for this Tyr mutation on an agouti background appears light brown
decreased eye pigmentation ( J:94077 )
• the ocular pigmentation of these mice appears altered compared to that of wild-type mice

vision/eye
decreased eye pigmentation ( J:94077 )
• the ocular pigmentation of these mice appears altered compared to that of wild-type mice




Genotype
MGI:5822839
cx2
Allelic
Composition		 A/?
Tyrc/Tyrem12Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
Tyrc mutation (79 available); any Tyr mutation (376 available)
Tyrem12Ove mutation (1 available); any Tyr mutation (376 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• the fur of these Tyr compound heterozygous mice on an agouti background appears very light brown

pigmentation
diluted coat color ( J:94077 )
• the fur of these Tyr compound heterozygous mice on an agouti background appears very light brown




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory