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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tyrem7Ove
endonuclease-mediated mutation 7, Paul Overbeek
MGI:5818810
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		A/?
Tyrem7Ove/Tyrem7Ove 		involves: C57BL/6 * FVB MGI:5818811
cx2
 		A/?
Tyrc/Tyrem7Ove 		involves: C57BL/6 * FVB MGI:5818819


Genotype
MGI:5818811
cx1
Allelic
Composition		 A/?
Tyrem7Ove/Tyrem7Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (80 available); any a mutation (468 available)
Tyrem7Ove mutation (1 available); any Tyr mutation (382 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• the fur of these mice exhibits nearly normal agouti coloration

pigmentation
diluted coat color ( J:94077 )
• the fur of these mice exhibits nearly normal agouti coloration
abnormal eye pigmentation ( J:94077 )
• mice homozygous for this Tyr promoter mutation exhibit nearly normal ocular pigmentation

vision/eye
abnormal eye pigmentation ( J:94077 )
• mice homozygous for this Tyr promoter mutation exhibit nearly normal ocular pigmentation




Genotype
MGI:5818819
cx2
Allelic
Composition		 A/?
Tyrc/Tyrem7Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (80 available); any a mutation (468 available)
Tyrc mutation (79 available); any Tyr mutation (382 available)
Tyrem7Ove mutation (1 available); any Tyr mutation (382 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• the fur of these compound Tyr mutant mice appears light agouti

pigmentation
diluted coat color ( J:94077 )
• the fur of these compound Tyr mutant mice appears light agouti




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory