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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Foxg1tm1.1(cre)Ddmo
targeted mutation 1.1, Dennis D M O'Leary
MGI:5818697
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1d(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu 		involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N MGI:7526488
cn2
 		Foxg1tm1.1(cre)Ddmo/0
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1aem1Knwea/Polr1atm1c(EUCOMM)Hmgu 		involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N MGI:7526484
cn3
 		Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1a(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu 		involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N MGI:7526487
cn4
 		Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1c(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu 		involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N MGI:7526489


Genotype
MGI:7526488
cn1
Allelic
Composition		 Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1d(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Genetic
Background		 involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1.1(cre)Ddmo mutation (1 available); any Foxg1 mutation (31 available)
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo mutation (10 available); any Gt(ROSA)26Sor mutation (1046 available)
Polr1atm1c(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (95 available)
Polr1atm1d(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
telencephalon hypoplasia ( J:335489 )
• in E12, E14 and E17 embryos




Genotype
MGI:7526484
cn2
Allelic
Composition		 Foxg1tm1.1(cre)Ddmo/0
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1aem1Knwea/Polr1atm1c(EUCOMM)Hmgu
Genetic
Background		 involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1.1(cre)Ddmo mutation (1 available); any Foxg1 mutation (31 available)
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo mutation (10 available); any Gt(ROSA)26Sor mutation (1046 available)
Polr1aem1Knwea mutation (0 available); any Polr1a mutation (95 available)
Polr1atm1c(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
telencephalon hypoplasia ( J:335489 )
• in E14 and E17 embryos
• normal in E12 embryos




Genotype
MGI:7526487
cn3
Allelic
Composition		 Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1a(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Genetic
Background		 involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1.1(cre)Ddmo mutation (1 available); any Foxg1 mutation (31 available)
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo mutation (10 available); any Gt(ROSA)26Sor mutation (1046 available)
Polr1atm1a(EUCOMM)Hmgu mutation (1 available); any Polr1a mutation (95 available)
Polr1atm1c(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
telencephalon hypoplasia ( J:335489 )
• in E12, E14 and E17 embryos




Genotype
MGI:7526489
cn4
Allelic
Composition		 Foxg1tm1.1(cre)Ddmo/Foxg1+
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1c(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Genetic
Background		 involves: 129S1/Sv * 129T/Sv * 129X1/SvJ * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1.1(cre)Ddmo mutation (1 available); any Foxg1 mutation (31 available)
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo mutation (10 available); any Gt(ROSA)26Sor mutation (1046 available)
Polr1atm1c(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (95 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
telencephalon hypoplasia ( J:335489 )
• in E12, E14 and E17 embryos




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory