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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tyrem3Ove
endonuclease-mediated mutation 3, Paul Overbeek
MGI:5817585
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tyrem3Ove/Tyrem3Ove involves: C57BL/6 * FVB MGI:5817586
ht2
 		Tyrc/Tyrem3Ove involves: C57BL/6 * FVB MGI:5817589


Genotype
MGI:5817586
hm1
Allelic
Composition		 Tyrem3Ove/Tyrem3Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrem3Ove mutation (1 available); any Tyr mutation (382 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
diluted coat color ( J:94077 )
• mice homozygous for this mutation exhibit very light fur pigmentation

pigmentation
diluted coat color ( J:94077 )
• mice homozygous for this mutation exhibit very light fur pigmentation

vision/eye




Genotype
MGI:5817589
ht2
Allelic
Composition		 Tyrc/Tyrem3Ove
Genetic
Background		 involves: C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tyrc mutation (79 available); any Tyr mutation (382 available)
Tyrem3Ove mutation (1 available); any Tyr mutation (382 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye

integument
absent coat pigmentation ( J:94077 )
• these compound heterozygotes have white fur and black eyes

pigmentation
absent coat pigmentation ( J:94077 )
• these compound heterozygotes have white fur and black eyes




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/07/2025
MGI 6.24 		The Jackson Laboratory