All Phenotypes Pik3r1<em1Btlr> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pik3r1^em1Btlr
endonuclease-mediated mutation 1, Bruce Beutler
MGI:5806486

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Kbtbd2^em1Btlr/Kbtbd2^em1Btlr Pik3r1^em1Btlr/Pik3r1^em1Btlr	Not Specified	MGI:5806515

Allelic Composition	Kbtbd2^em1Btlr/Kbtbd2^em1Btlr Pik3r1^em1Btlr/Pik3r1^em1Btlr
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kbtbd2^em1Btlr mutation (0 available); any Kbtbd2 mutation (49 available)
Pik3r1^em1Btlr mutation (0 available); any Pik3r1 mutation (55 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased circulating glucose level ( J:236520 )

• 11 week old male mice exhibit decreased serum glucose levels compared with Kbtbd2^em1Btlr homozygotes

decreased circulating insulin level ( J:236520 )

• 11 week old male mice exhibit decreased serum insulin levels compared with Kbtbd2^em1Btlr homozygotes

increased insulin sensitivity ( J:236520 )

• in 11 week old male compared with Kbtbd2^em1Btlr homozygotes

growth/size/body

increased body fat mass ( J:236520 )

• 11 week old male mice exhibit increased fat weight compared with Kbtbd2^em1Btlr homozygotes

increased body weight ( J:236520 )

• 11 week old male mice exhibit increased body weight compared with Kbtbd2^em1Btlr homozygotes

adipose tissue

increased body fat mass ( J:236520 )

• 11 week old male mice exhibit increased fat weight compared with Kbtbd2^em1Btlr homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23