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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptpn6em1.1Shoy
endonuclease-mediated mutation 1.1, Sho Yamasaki
MGI:5805709
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ptpn6em1.1Shoy/Ptpn6em1.1Shoy involves: C57BL/6 MGI:5805814


Genotype
MGI:5805814
hm1
Allelic
Composition		 Ptpn6em1.1Shoy/Ptpn6em1.1Shoy
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn6em1.1Shoy mutation (0 available); any Ptpn6 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased thymocyte number ( J:236298 )
• reduced CD4+ single positive thymocytes when transferred into Cd3etm1Mal homozygotes

endocrine/exocrine glands
decreased thymocyte number ( J:236298 )
• reduced CD4+ single positive thymocytes when transferred into Cd3etm1Mal homozygotes

hematopoietic system
decreased thymocyte number ( J:236298 )
• reduced CD4+ single positive thymocytes when transferred into Cd3etm1Mal homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory