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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		+
wild type
MGI:5790349
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Del(1Aim2-Ifi205)1Stsn/+
Trex1tm1Tld/Trex1tm1Tld 		involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N MGI:5790350


Genotype
MGI:5790350
cx1
Allelic
Composition		 Del(1Aim2-Ifi205)1Stsn/+
Trex1tm1Tld/Trex1tm1Tld
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(1Aim2-Ifi205)1Stsn mutation (1 available); any Del(1Aim2-Ifi205)1Stsn mutation (1 available)
Trex1tm1Tld mutation (3 available); any Trex1 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

digestive/alimentary system
stomach inflammation ( J:234263 )
• glandular stomach inflammation

immune system
increased autoantibody level ( J:234263 )
• autoantibodies against heart tissue antigens are detected
stomach inflammation ( J:234263 )
• glandular stomach inflammation
myositis ( J:234263 )
• inflammation is observed in multiple tissues including heart, tongue, skeletal muscle, glandular stomach, and kidney

mortality/aging
premature death ( J:234263 )
• mice develop a lethal autoimmune disease; death begins at 5 weeks of age
• all mice die by 30 weeks

muscle
myositis ( J:234263 )
• inflammation is observed in multiple tissues including heart, tongue, skeletal muscle, glandular stomach, and kidney

renal/urinary system




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory