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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ern2M2Btlr
mutation 2, Bruce Beutler
MGI:5789538
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ern2M2Btlr/Ern2M2Btlr C57BL/6J-Ern2M2Btlr MGI:5789621


Genotype
MGI:5789621
hm1
Allelic
Composition		 Ern2M2Btlr/Ern2M2Btlr
Genetic
Background		 C57BL/6J-Ern2M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ern2M2Btlr mutation (0 available); any Ern2 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:234237 )
• mice showed weight loss at day 10 after treatment with dextran sulfate sodium (DSS)-containing water, indicating susceptibility to DSS-induced colitis

immune system
increased susceptibility to induced colitis ( J:234237 )
• mice showed weight loss at day 10 after treatment with dextran sulfate sodium (DSS)-containing water, indicating susceptibility to DSS-induced colitis




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory