Phenotypes associated with this allele

• Allele Symbol: Agbl5^em1Zfa
• Allele Name: endonuclease-mediated mutation 1, Zusen Fan
• Allele ID: MGI:5787969
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Agbl5^em1Zfa/Agbl5^em1Zfa	Not Specified	MGI:5898024

Genotype
MGI:5898024

hm1

• Allelic Composition: Agbl5^em1Zfa/Agbl5^em1Zfa
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to Herpesvirales infection ( J:231311 )

• following herpes simplex virus (HSV) infection, mice exhibit increased mortality and viral load with decreased IFN alpha and beta compared with wild-type mice

increased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:231311 )

• following herpes simplex virus (HSV) infection, mice exhibit increased mortality compared with wild-type mice

increased susceptibility to Poxviridae infection ( J:231311 )

• following vaccinia virus (VACV) infection, mice exhibit increased mortality and viral load with decreased IFN alpha and beta compared with wild-type mice

increased susceptibility to Poxviridae infection induced morbidity/mortality ( J:231311 )

• following vaccinia virus (VACV) infection, mice exhibit increased mortality compared with wild-type mice

mortality/aging

increased susceptibility to Herpesvirales infection induced morbidity/mortality ( J:231311 )

• following herpes simplex virus (HSV) infection, mice exhibit increased mortality compared with wild-type mice

increased susceptibility to Poxviridae infection induced morbidity/mortality ( J:231311 )

• following vaccinia virus (VACV) infection, mice exhibit increased mortality compared with wild-type mice