Phenotypes associated with this allele

• Allele Symbol: Scn8a^m11J
• Allele Name: mutation 11, Jackson
• Allele ID: MGI:5771986
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Scn8a^m11J/Scn8a^m11J	B6.Cg-Scn8a^m11J/GrsrJ	MGI:5771988

Genotype
MGI:5771988

hm1

• Allelic Composition: Scn8a^m11J/Scn8a^m11J
• Genetic Background: B6.Cg-Scn8a^m11J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:231578 )

• all homozygotes die by approximately 3 weeks of age

muscle

impaired muscle relaxation ( J:231578 )

behavior/neurological

ataxia ( J:231578 )

paralysis ( J:231578 )

• rapidly progressing paralysis, most notably in the hind legs

hindlimb paralysis ( J:231578 )

growth/size/body

decreased body size ( J:231578 )