All Phenotypes Egr1<tm1b(NCOM)Mfgc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Egr1^{tm1b(NCOM)Mfgc}
targeted mutation 1b, Mammalian Functional Genomics Centre
MGI:5766183

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Egr1^{tm1b(NCOM)Mfgc}/Egr1^{tm1b(NCOM)Mfgc}	C57BL/6N-Egr1^{tm1b(NCOM)Mfgc}/Tcp	MGI:5797501
ht2	Egr1^{tm1b(NCOM)Mfgc}/Egr1⁺	C57BL/6N-Egr1^{tm1b(NCOM)Mfgc}/Tcp	MGI:5797500

Allelic Composition	Egr1^{tm1b(NCOM)Mfgc}/Egr1^{tm1b(NCOM)Mfgc}
Genetic Background	C57BL/6N-Egr1^{tm1b(NCOM)Mfgc}/Tcp
Cell Lines	M00043_C_384W_A04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egr1^{tm1b(NCOM)Mfgc} mutation (1 available); any Egr1 mutation (23 available)

Data Sources

IMPC Data for Egr1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

abnormal neural tube closure ( J:211773 )

IMPC - TCP

endocrine/exocrine glands

absent seminal vesicle ( J:211773 )

IMPC - TCP

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - TCP

abnormal embryo size ( J:211773 )

IMPC - TCP

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - TCP

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - TCP

abnormal forebrain development ( J:211773 )

IMPC - TCP

abnormal hindbrain development ( J:211773 )

IMPC - TCP

abnormal midbrain development ( J:211773 )

IMPC - TCP

abnormal optic disk morphology ( J:211773 )

IMPC - TCP

reproductive system

absent seminal vesicle ( J:211773 )

IMPC - TCP

small uterus ( J:211773 )

IMPC - TCP

female infertility ( J:211773 )

IMPC - TCP

male infertility ( J:211773 )

IMPC - TCP

vision/eye

abnormal optic disk morphology ( J:211773 )

IMPC - TCP

Allelic Composition	Egr1^{tm1b(NCOM)Mfgc}/Egr1⁺
Genetic Background	C57BL/6N-Egr1^{tm1b(NCOM)Mfgc}/Tcp
Cell Lines	M00043_C_384W_A04

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Egr1^{tm1b(NCOM)Mfgc} mutation (1 available); any Egr1 mutation (23 available)

Data Sources

IMPC Data for Egr1

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

growth/size/body

decreased body length ( J:211773 )

IMPC - TCP

hematopoietic system

increased lymphocyte cell number ( J:211773 )

IMPC - TCP

immune system

increased lymphocyte cell number ( J:211773 )

IMPC - TCP

limbs/digits/tail

short tibia ( J:211773 )

IMPC - TCP

skeleton

short tibia ( J:211773 )

IMPC - TCP

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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