All Phenotypes Grm6<nob7> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Grm6^nob7
no b wave 7
MGI:5754842

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grm6^nob7/Grm6^nob7	C57BL/6J-Grm6^nob7	MGI:5754843
ht2	Grm6^nob3/Grm6^nob7	involves: C57BL/6J * C57BL/10J	MGI:5755378

Allelic Composition	Grm6^nob7/Grm6^nob7
Genetic Background	C57BL/6J-Grm6^nob7

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grm6^nob7 mutation (0 available); any Grm6 mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

decreased b-wave amplitude ( J:229885 )

• electroretinography has no b wave component under dark or light adapted conditions

abnormal cone electrophysiology ( J:229885 )

• photopic b waves are absent and cone ERGs are electronegative

abnormal rod electrophysiology ( J:229885 )

• scotopic b waves are absent, and the a wave is followed by a negative component, slow PIII

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
congenital stationary night blindness 1B		DOID:0110865	OMIM:257270	J:229885

Allelic Composition	Grm6^nob3/Grm6^nob7
Genetic Background	involves: C57BL/6J * C57BL/10J