All Phenotypes Nr1d2<tm1.1Pbrc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Nr1d2^tm1.1Pbrc
targeted mutation 1.1, Pennington Biomedical Research Center
MGI:5752902

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nr1d2^tm1.1Pbrc/Nr1d2^tm1.1Pbrc	involves: C57BL/6J	MGI:5755520

Allelic Composition	Nr1d2^tm1.1Pbrc/Nr1d2^tm1.1Pbrc
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr1d2^tm1.1Pbrc mutation (0 available); any Nr1d2 mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired behavioral response to xenobiotic ( J:225389 )

• in the marble burying assay, mice treated with the synthetic REV-ERB agonist SR9011 fail to display an anxiolytic response and bury a similar number of marbles relative to vehicle-treated mice

increased anxiety-related response ( J:225389 )

• in the marble burying assay, mice bury significantly more marbles than wild-type controls, indicating increased anxiety-like behavior

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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