Analysis Tools
cardiovascular system
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• sarcoplasmic reticulum Ca2+ content at 5.0 mM is higher than controls
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• increased contraction amplitude in response to elevation of Ca2+ as compared to controls
• at 0.6 mM [Ca2+] myocytes shorten less than controls
• at 5.0 mM [Ca2+] myocytes contract more than controls
• at 1.8 mM [Ca2+] contraction amplitudes are similar controls
• maximal shortening and relengthening velocities are both slower (at 0.6) and faster (at 5.0) than controls
• systolic and transient amplitudes are both lower (at 0.6) and higher (at 5.0) than controls, however, there is no difference in diastolic amplitude
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• increased INaCa (NCX1 current) in myocytes as voltage becomes more positive as compared to controls
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muscle
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• sarcoplasmic reticulum Ca2+ content at 5.0 mM is higher than controls
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• increased contraction amplitude in response to elevation of Ca2+ as compared to controls
• at 0.6 mM [Ca2+] myocytes shorten less than controls
• at 5.0 mM [Ca2+] myocytes contract more than controls
• at 1.8 mM [Ca2+] contraction amplitudes are similar controls
• maximal shortening and relengthening velocities are both slower (at 0.6) and faster (at 5.0) than controls
• systolic and transient amplitudes are both lower (at 0.6) and higher (at 5.0) than controls, however, there is no difference in diastolic amplitude
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nervous system
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• action potential duration is prolonged at 50% and 90% repolarization as compared to controls
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