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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prdm13tm1.1Tfur
targeted mutation 1.1, Takahisa Furukawa
MGI:5752205
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Prdm13tm1.1Tfur/Prdm13tm1.1Tfur
Tg(Dkk3-cre)D9Tfur/0 		involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N MGI:5780207


Genotype
MGI:5780207
cn1
Allelic
Composition		 Prdm13tm1.1Tfur/Prdm13tm1.1Tfur
Tg(Dkk3-cre)D9Tfur/0
Genetic
Background		 involves: C3H * C57BL/6 * C57BL/6J * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm13tm1.1Tfur mutation (1 available); any Prdm13 mutation (45 available)
Tg(Dkk3-cre)D9Tfur mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
decreased amacrine cell number ( J:222242 )
• specific reduction in the number of GABAergic or glycinergic amacrine cells at P14
abnormal retina inner plexiform layer morphology ( J:222242 )
• loss of the S2/S3 border neurite bundle labeled by anti-Calretinin antibodies in the IPL at P14

behavior/neurological
abnormal optokinetic reflex ( J:222242 )
• at 2 months of age, mice exhibit higher responses to visual stimuli in initial optokinetic responses with a broader range of spatial and temporal frequencies than those observed in controls

nervous system
decreased amacrine cell number ( J:222242 )
• specific reduction in the number of GABAergic or glycinergic amacrine cells at P14




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory