Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk13em1(IMPC)H mutation
(2 available);
any
Kcnk13 mutation
(22 available)
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Data Sources
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hematopoietic system
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IMPC - HAR
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IMPC - HAR
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immune system
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnk13em1(IMPC)H mutation
(2 available);
any
Kcnk13 mutation
(22 available)
|
|
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nervous system
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• much less complex ramification pattern, both in brain slices and in vivo brain
• significantly decreased number of processes, smaller total process length, and fewer process intersections with shells at different radii from the cell soma
• no change in tiling pattern or mean microglial density in tissue
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• initial rate of surveillance reduced (41% in brain slices and 45% in brain in vivo) and cumulative area (in maximum intensity projections) surveyed after an hour reduced (31% and 38%)
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immune system
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• much less complex ramification pattern, both in brain slices and in vivo brain
• significantly decreased number of processes, smaller total process length, and fewer process intersections with shells at different radii from the cell soma
• no change in tiling pattern or mean microglial density in tissue
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• initial rate of surveillance reduced (41% in brain slices and 45% in brain in vivo) and cumulative area (in maximum intensity projections) surveyed after an hour reduced (31% and 38%)
|
hematopoietic system
|
|
• much less complex ramification pattern, both in brain slices and in vivo brain
• significantly decreased number of processes, smaller total process length, and fewer process intersections with shells at different radii from the cell soma
• no change in tiling pattern or mean microglial density in tissue
|
|
|
• initial rate of surveillance reduced (41% in brain slices and 45% in brain in vivo) and cumulative area (in maximum intensity projections) surveyed after an hour reduced (31% and 38%)
|
Analysis Tools