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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Prnp-MAPT)#Lgn
transgene insertion, Li Gan
MGI:5708386
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Prnp-MAPT)#Lgn/0 involves: C57BL/6 * FVB/N MGI:5829784


Genotype
MGI:5829784
tg1
Allelic
Composition
Tg(Prnp-MAPT)#Lgn/0
Genetic
Background
involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• astrogliosis in the dentate gyrus
• however, mice do not show tau accumulation in hippocampal mossy fibers, normal long term potentiation and synaptic plasticity in the hippocampus, and normal pattern separation memory in an object-context discrimination test





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory