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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kcnt1tm1.1Acsc
targeted mutation 1.1, Achim Schmidtko
MGI:5708320
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc
Tg(Scn10a-cre)1Rkun/0 		involves: BALB/cJ * C57BL/6 * C57BL/6N * DBA/2 MGI:5896605


Genotype
MGI:5896605
cn1
Allelic
Composition		 Kcnt1tm1.1Acsc/Kcnt1tm1.1Acsc
Tg(Scn10a-cre)1Rkun/0
Genetic
Background		 involves: BALB/cJ * C57BL/6 * C57BL/6N * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnt1tm1.1Acsc mutation (0 available); any Kcnt1 mutation (70 available)
Tg(Scn10a-cre)1Rkun mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal mechanical nociception ( J:218978 )
• increased mechanical hypersensitivity after spared nerve injury used to induce a neuropathic pain model
• however, inflammatory pain behavior is normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory